Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006147.4

p.R339G

c.1015A>G

Surrounding Variants

4 papers

NM_006147.4

p.R339I

c.1016G>T

1 paper

NM_006147.4

p.E338D

c.1014G>C

2 papers

NM_006147.4

p.I337fs

c.1009_1010fs

2 papers

NM_006147.4

p.I337T

c.1010T>C

2 papers

NM_006147.4

p.I337_Q340delFs

c.1011_1020del10

2 papers

NM_006147.4

p.L336R

c.1007T>G

1 paper

NM_006147.4

p.V332_L336delFs

c.994_1006del13

1 paper

NM_006147.4

p.A333T

c.997G>A

1 paper

NM_006147.4

p.V332fs

c.994_995fs

6 papers

NM_006147.4

p.L345P

c.1034T>C

1 paper

NM_006147.4

p.F346L

c.1036T>C

2 papers

NM_006147.4

p.V332I

c.994G>A