Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_006147.4

p.G325E

c.974G>A

Surrounding Variants

2 papers

NM_006147.4

p.G325V

c.974G>T

1 paper

NM_006147.4

p.S324insFs

c.970_971insTG

1 paper

NM_006147.4

p.S324P

c.970T>C

1 paper

NM_006147.4

p.W323*

c.969G>A

1 paper

NM_006147.4

p.W323*

c.968G>A

3 papers

NM_006147.4

p.C327*

c.981T>A

1 paper

NM_006147.4

p.V321_Y322del2

c.961_965del6

1 paper

NM_006147.4

p.A328T

c.982G>A

1 paper

NM_006147.4

p.V321_Y322delFs

c.961_965del5

3 papers

NM_006147.4

p.Y322C

c.965A>G

1 paper

NM_006147.4

p.V321_Y322Fs

c.961_965delinsCFs

1 paper

NM_006147.4

p.Y322N

c.964T>A