Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_006147.4

p.V321M

c.961G>A

Surrounding Variants

1 paper

NM_006147.4

p.V321fs

c.961_962fs

4 papers

NM_006147.4

p.K320N

c.960G>T

4 papers

NM_006147.4

p.K320N

c.960G>C

1 paper

NM_006147.4

p.Y322N

c.964T>A

7 papers

NM_006147.4

p.K320E

c.958A>G

3 papers

NM_006147.4

p.C319*

c.957C>A

3 papers

NM_006147.4

p.Y322C

c.965A>G

1 paper

NM_006147.4

p.V321_Y322Fs

c.961_965delinsCFs

1 paper

NM_006147.4

p.V321_Y322delFs

c.961_965del5

2 papers

NM_006147.4

p.C319R

c.955T>C

1 paper

NM_006147.4

p.V321_Y322del2

c.961_965del6

5 papers

NM_006147.4

p.Q318H

c.954G>T