Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006147.4

p.A310_A313del4

c.928_938del12

Surrounding Variants

1 paper

NM_006147.4

p.A313V

c.938C>T

1 paper

NM_006147.4

p.R315K

c.944G>A

1 paper

NM_006147.4

p.R315R

c.945G>A

1 paper

NM_006147.4

p.I311T

c.932T>C

1 paper

NM_006147.4

p.I311V

c.931A>G

2 papers

NM_006147.4

p.C317Y

c.950G>A

3 papers

NM_006147.4

p.Q318*

c.952C>T

3 papers

NM_006147.4

p.Q318P

c.953A>C

5 papers

NM_006147.4

p.Q318H

c.954G>T

5 papers

NM_006147.4

p.Q318H

c.954G>C

2 papers

NM_006147.4

p.C319R

c.955T>C

1 paper

NM_006147.4

p.G308D

c.923G>A