Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006147.4

p.P268P

c.804C>G

Surrounding Variants

1 paper

NM_006147.4

p.V269insFs

c.805_806insT

1 paper

NM_006147.4

p.P268insFs

c.803dupC

2 papers

NM_006147.4

p.V269I

c.805G>A

3 papers

NM_006147.4

p.P268L

c.803C>T

1 paper

NM_006147.4

p.P268S

c.802C>T

1 paper

NM_006147.4

p.G267A

c.800G>C

3 papers

NM_006147.4

p.G267C

c.799G>T

1 paper

NM_006147.4

p.L265delFs

c.795delG

4 papers

NM_006147.4

p.L265fs

c.793_794fs

1 paper

NM_006147.4

p.Q273E

c.817C>G

5 papers

NM_006147.4

p.Q273R

c.818A>G

3 papers

NM_006147.4

p.Q273H

c.819G>T