Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006147.4

p.G254E

c.761G>A

Surrounding Variants

5 papers

NM_006147.4

p.Y253*

c.759T>G

1 paper

NM_006147.4

p.Y253Y

c.759T>C

5 papers

NM_006147.4

p.Y253*

c.759T>A

1 paper

NM_006147.4

p.D255Y

c.763G>T

6 papers

NM_006147.4

p.F252L

c.756C>G

7 papers

NM_006147.4

p.F252L

c.756C>A

3 papers

NM_006147.4

p.F252S

c.755T>C

1 paper

NM_006147.4

p.F252Y

c.755T>A

1 paper

NM_006147.4

p.F252V

c.754T>G

6 papers

NM_006147.4

p.F252L

c.754T>C

1 paper

NM_006147.4

p.G257fs

c.769_770fs

6 papers

NM_006147.4

p.L251P

c.752T>C