Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006147.4

p.P246S

c.736C>T

Surrounding Variants

1 paper

NM_006147.4

p.P246fs

c.736_737fs

1 paper

NM_006147.4

p.N245_P246delins

c.735_736delinsTT

1 paper

NM_006147.4

p.P246delFs

c.737delG

1 paper

NM_006147.4

p.G248C

c.742G>T

1 paper

NM_006147.4

p.G248insFs

c.743_744ins4

3 papers

NM_006147.4

p.G248A

c.743G>C

1 paper

NM_001206696.2

p.V148E

c.443T>A

4 papers

NM_006147.4

p.G248fs

c.742_743fs

1 paper

NM_006147.4

p.C249R

c.745T>C

1 paper

NM_006147.4

p.V243M

c.727G>A

1 paper

NM_006147.4

p.Q239_T242del0

c.716_724del9

10 papers

NM_006147.4

p.R250*

c.748C>T