Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006147.4

p.K229fs

c.685_686fs

Surrounding Variants

3 papers

NM_006147.4

p.I228T

c.683T>C

1 paper

NM_006147.4

p.K229fs

c.685_686fs

1 paper

NM_006147.4

p.K229delFs

c.686delT

3 papers

NM_006147.4

p.F230L

c.688T>C

1 paper

NM_006147.4

p.K229delFs

c.687delC

1 paper

NM_006147.4

p.I228F

c.682A>T

3 papers

NM_006147.4

p.F230L

c.690T>G

3 papers

NM_006147.4

p.F230L

c.690T>A

1 paper

NM_006147.4

p.D227H

c.679G>C

1 paper

NM_006147.4

p.Q231*

c.691C>T

2 papers

NM_006147.4

p.F230delFs

c.690delA

1 paper

NM_006147.4

p.Y232fs

c.694_695fs