Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006147.4

p.T224S

c.671C>G

Surrounding Variants

1 paper

NM_006147.4

p.T224S

c.670A>T

7 papers

NM_006147.4

p.D225H

c.673G>C

3 papers

NM_006147.4

p.M223Splc

c.668-1G>A

2 papers

NM_006147.4

p.M223Splc

c.668-3C>A

1 paper

NM_006147.4

p.M223Splc

c.668-4G>T

3 papers

NM_006147.4

p.M223Splc

c.668-5T>G

1 paper

NM_006147.4

p.D227H

c.679G>C

1 paper

NM_006147.4

p.M223Splc

c.668-8C>G

1 paper

NM_006147.4

p.I228F

c.682A>T

3 papers

NM_006147.4

p.I228T

c.683T>C

1 paper

NM_006147.4

p.K229fs

c.685_686fs

1 paper

NM_006147.4

p.K229fs

c.685_686fs