Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006147.4

p.P107T

c.319C>A

Surrounding Variants

1 paper

NM_006147.4

p.P107_V108delFs

c.321_322delCT

1 paper

NM_006147.4

p.P104_M105delFs

c.310_313del4

1 paper

NM_006147.4

p.V108fs

c.322_323fs

2 papers

NM_006147.4

p.M105V

c.313A>G

2 papers

NM_006147.4

p.K109T

c.326A>C

1 paper

NM_006147.4

p.K109N

c.327G>T

1 paper

NM_006147.4

p.K109N

c.327G>C

4 papers

NM_006147.4

p.I110L

c.328A>T

4 papers

NM_006147.4

p.I110L

c.328A>C

1 paper

NM_006147.4

p.I110T

c.329T>C

5 papers

NM_006147.4

p.Y111H

c.331T>C

3 papers

NM_006147.4

p.Y111C

c.332A>G