Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_006147.4

p.D98V

c.293A>T

Surrounding Variants

1 paper

NM_006147.4

p.D98G

c.293A>G

1 paper

NM_006147.4

p.D98E

c.294T>G

1 paper

NM_006147.4

p.D98E

c.294T>A

8 papers

NM_006147.4

p.D98H

c.292G>C

3 papers

NM_006147.4

p.G99S

c.295G>A

6 papers

NM_006147.4

p.Y97C

c.290A>G

1 paper

NM_006147.4

p.G99G

c.297C>T

9 papers

NM_006147.4

p.T100A

c.298A>G

2 papers

NM_006147.4

p.T100_K101insT

c.298_302ins3

3 papers

NM_006147.4

p.T100I

c.299C>T

1 paper

NM_006147.4

p.T100insFs

c.300dupC

3 papers

NM_006147.4

p.L95P

c.284T>C