Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006147.4

p.E92K

c.274G>A

Surrounding Variants

7 papers

NM_006147.4

p.E92*

c.274G>T

3 papers

NM_006147.4

p.E92V

c.275A>T

1 paper

NM_006147.4

p.R91S

c.273A>T

1 paper

NM_006147.4

p.R91S

c.273A>C

1 paper

NM_006147.4

p.F93L

c.277T>C

4 papers

NM_006147.4

p.S90I

c.269G>T

1 paper

NM_006147.4

p.S90T

c.269G>C

5 papers

NM_006147.4

p.F93F

c.279C>T

1 paper

NM_006147.4

p.F93L

c.279C>G

1 paper

NM_006147.4

p.F93L

c.279C>A

6 papers

NM_006147.4

p.S90G

c.268A>G

1 paper

NM_006147.4

p.N94D

c.280A>G