Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_006147.4

p.N88S

c.263A>G

Surrounding Variants

3 papers

NM_006147.4

p.N88I

c.263A>T

1 paper

NM_006147.4

p.N88K

c.264T>G

1 paper

NM_006147.4

p.N88K

c.264T>A

3 papers

NM_006147.4

p.N88Y

c.262A>T

4 papers

NM_006147.4

p.N88D

c.262A>G

7 papers

NM_006147.4

p.N88H

c.262A>C

1 paper

NM_006147.4

p.K89*

c.265A>T

8 papers

NM_006147.4

p.K89E

c.265A>G

1 paper

NM_006147.4

p.L87P

c.260T>C

2 papers

NM_006147.4

p.K89N

c.267G>C

4 papers

NM_006147.4

p.L87F

c.259C>T

6 papers

NM_006147.4

p.S90G

c.268A>G