Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

61 papers

NM_006147.4

p.R84C

c.250C>T

Surrounding Variants

10 papers

NM_006147.4

p.R84G

c.250C>G

2 papers

NM_006147.4

p.R84S

c.250C>A

5 papers

NM_006147.4

p.R84L

c.251G>T

6 papers

NM_006147.4

p.R84P

c.251G>C

23 papers

NM_006147.4

p.R84H

c.251G>A

2 papers

NM_006147.4

p.L83R

c.248T>G

1 paper

NM_006147.4

p.R84R

c.252C>A

2 papers

NM_006147.4

p.C85R

c.253T>C

2 papers

NM_006147.4

p.L83V

c.247C>G

5 papers

NM_006147.4

p.C85F

c.254G>T

2 papers

NM_006147.4

p.Q82H

c.246G>T

2 papers

NM_006147.4

p.Q82H

c.246G>C