Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006147.4

p.A77D

c.230C>A

Surrounding Variants

3 papers

NM_006147.4

p.K78E

c.232A>G

3 papers

NM_006147.4

p.P76L

c.227C>T

13 papers

NM_006147.4

p.P76S

c.226C>T

2 papers

NM_006147.4

p.W79R

c.235T>C

2 papers

NM_006147.4

p.W79R

c.235T>A

2 papers

NM_006147.4

p.D75G

c.224A>G

2 papers

NM_006147.4

p.D75insFs

c.223dupG

1 paper

NM_006147.4

p.K80E

c.238A>G

5 papers

NM_006147.4

p.P74L

c.221C>T

3 papers

NM_006147.4

p.P74R

c.221C>G

4 papers

NM_006147.4

p.K80R

c.239A>G

1 paper

NM_006147.4

p.A81G

c.242C>G