Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_006147.4

p.Y67*

c.201C>A

Surrounding Variants

4 papers

NM_006147.4

p.Y67*

c.201C>G

6 papers

NM_006147.4

p.Q68*

c.202C>T

2 papers

NM_006147.4

p.Y67C

c.200A>G

2 papers

NM_006147.4

p.K66_Y67delins

c.197_199delinsGGG

2 papers

NM_006147.4

p.E69K

c.205G>A

1 paper

NM_006147.4

p.K66R

c.197A>G

7 papers

NM_006147.4

p.K66T

c.197A>C

5 papers

NM_006147.4

p.K66*

c.196A>T

2 papers

NM_006147.4

p.E69G

c.206A>G

3 papers

NM_006147.4

p.G65V

c.194G>T

2 papers

NM_006147.4

p.G70W

c.208G>T

8 papers

NM_006147.4

p.G70R

c.208G>C