Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006147.4

p.F57fs

c.169_170fs

Surrounding Variants

3 papers

NM_006147.4

p.F57L

c.171T>G

3 papers

NM_006147.4

p.F57L

c.171T>A

3 papers

NM_006147.4

p.F57L

c.169T>C

1 paper

NM_006147.4

p.K58N

c.174G>C

3 papers

NM_006147.4

p.K58K

c.174G>A

3 papers

NM_006147.4

p.I56T

c.167T>C

2 papers

NM_006147.4

p.K58_A59Splc

c.174+1G>T

4 papers

NM_006147.4

p.K58_A59Splc

c.174+1G>A

4 papers

NM_006147.4

p.I56fs

c.166_167fs

4 papers

NM_006147.4

p.T55delFs

c.165delG

2 papers

NM_006147.4

p.T55insFs

c.163dupA

1 paper

NM_006147.4

p.T55A

c.163A>G