Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006147.4

p.S33C

c.98C>G

Surrounding Variants

1 paper

NM_006147.4

p.S33A

c.97T>G

4 papers

NM_006147.4

p.K34E

c.100A>G

2 papers

NM_006147.4

p.K34insFs

c.100_101insT

1 paper

NM_006147.4

p.G21_S33del13

c.61_98del39

2 papers

NM_006147.4

p.K34fs

c.100_101fs

4 papers

NM_006147.4

p.K34T

c.101A>C

2 papers

NM_006147.4

p.S33_K34delFs

c.99_100delTA

3 papers

NM_006147.4

p.R35C

c.103C>T

4 papers

NM_006147.4

p.R35P

c.104G>C

1 paper

NM_006147.4

p.R31T

c.92G>C

2 papers

NM_006147.4

p.R35H

c.104G>A

3 papers

NM_006147.4

p.F36S

c.107T>C