Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006147.4

p.R31T

c.92G>C

Surrounding Variants

1 paper

NM_006147.4

p.H30N

c.88C>A

1 paper

NM_006147.4

p.H30fs

c.88_89fs

1 paper

NM_006147.4

p.S33A

c.97T>G

1 paper

NM_006147.4

p.L29R

c.86T>G

1 paper

NM_006147.4

p.S33C

c.98C>G

1 paper

NM_006147.4

p.W28*

c.84G>A

4 papers

NM_006147.4

p.K34E

c.100A>G

2 papers

NM_006147.4

p.K34insFs

c.100_101insT

1 paper

NM_006147.4

p.G21_S33del13

c.61_98del39

2 papers

NM_006147.4

p.K34fs

c.100_101fs

3 papers

NM_006147.4

p.W28L

c.83G>T

1 paper

NM_006147.4

p.W28*

c.83G>A