Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_006147.4

p.G25V

c.74G>T

Surrounding Variants

4 papers

NM_006147.4

p.G25A

c.74G>C

1 paper

NM_006147.4

p.P24P

c.72T>C

2 papers

NM_006147.4

p.G25insFs

c.75dupG

3 papers

NM_006147.4

p.L26P

c.77T>C

3 papers

NM_006147.4

p.P24L

c.71C>T

1 paper

NM_006147.4

p.P24S

c.70C>T

1 paper

NM_006147.4

p.G21_Y23del3

c.61_68del9

1 paper

NM_006147.4

p.Y23Y

c.69C>T

5 papers

NM_006147.4

p.Y23*

c.69C>G

5 papers

NM_006147.4

p.Y23*

c.69C>A

1 paper

NM_006147.4

p.I27N

c.80T>A

2 papers

NM_006147.4

p.W28G

c.82T>G