Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006147.4

p.S20C

c.58A>T

Surrounding Variants

3 papers

NM_006147.4

p.S20N

c.59G>A

3 papers

NM_006147.4

p.D19G

c.56A>G

1 paper

NM_006147.4

p.D19delFs

c.55delC

1 paper

NM_006147.4

p.D19N

c.55G>A

6 papers

NM_006147.4

p.V18A

c.53T>C

8 papers

NM_006147.4

p.V18M

c.52G>A

2 papers

NM_006147.4

p.L22F

c.64C>T

11 papers

NM_006147.4

p.L22P

c.65T>C

2 papers

NM_006147.4

p.Q17_L22delFs

c.49_64del16

4 papers

NM_006147.4

p.Q17fs

c.49_50fs

1 paper

NM_006147.4

p.Q17insFs

c.50dupA

2 papers

NM_006147.4

p.Q17R

c.50A>G