Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

11 papers

NM_006147.4

p.A16V

c.47C>T

Surrounding Variants

2 papers

NM_006147.4

p.V15fs

c.43_44fs

2 papers

NM_006147.4

p.Q17R

c.50A>G

5 papers

NM_006147.4

p.Q17P

c.50A>C

2 papers

NM_006147.4

p.V15insFs

c.43_44ins4

4 papers

NM_006147.4

p.Q17fs

c.49_50fs

1 paper

NM_006147.4

p.Q17insFs

c.50dupA

8 papers

NM_006147.4

p.V18M

c.52G>A

1 paper

NM_006147.4

p.L14delins

c.41_42delinsGT

1 paper

NM_006147.4

p.L14R

c.41T>G

6 papers

NM_006147.4

p.V18A

c.53T>C

3 papers

NM_006147.4

p.W13C

c.39G>T

3 papers

NM_006147.4

p.W13C

c.39G>C