Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_006147.4

p.W13*

c.39G>A

Surrounding Variants

3 papers

NM_006147.4

p.W13C

c.39G>T

3 papers

NM_006147.4

p.W13C

c.39G>C

2 papers

NM_006147.4

p.W13*

c.38G>A

1 paper

NM_006147.4

p.L14R

c.41T>G

1 paper

NM_006147.4

p.L14delins

c.41_42delinsGT

2 papers

NM_006147.4

p.V15insFs

c.43_44ins4

5 papers

NM_006147.4

p.P12L

c.35C>T

1 paper

NM_006147.4

p.P12H

c.35C>A

1 paper

NM_006147.4

p.P12A

c.34C>G

1 paper

NM_006147.4

p.R7_K11delFs

c.21_33del13

2 papers

NM_006147.4

p.V15fs

c.43_44fs

1 paper

NM_006147.4

p.K11M

c.32A>T