Varaico: Literature-Extracted Genetic Variants

Gene:IRS2
Variant:p.V775insFs

IRS2

613 papers

RefSeq Summary

This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adapto...

Pfam Domains

PHaa 31–144UCSCPH domain
IRSaa 200–295UCSCPTB domain (IRS-1 type)

Gene Aliases

HGNC Name

insulin receptor substrate 2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003749.3
p.V775insFs
c.2324_2325ins8
Surrounding Variants
1 paper
NM_003749.3
p.V775I
c.2323G>A
1 paper
NM_003749.3
p.S772R
c.2316C>G
1 paper
NM_003749.3
p.S772R
c.2316C>A
1 paper
NM_003749.3
p.S772R
c.2314A>C
1 paper
NM_003749.3
p.S770F
c.2309C>T
1 paper
NM_003749.3
p.S770P
c.2308T>C
2 papers
NM_003749.3
p.D782N
c.2344G>A
1 paper
NM_003749.3
p.F783L
c.2347T>C
1 paper
NM_003749.3
p.L767L
c.2301C>A
1 paper
NM_003749.3
p.L767R
c.2300T>G
1 paper
NM_003749.3
p.F783L
c.2349C>G
1 paper
NM_003749.3
p.F783L
c.2349C>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."