Varaico: Literature-Extracted Genetic Variants

Gene:IRS2
Variant:p.A701_V702ins0

IRS2

613 papers

RefSeq Summary

This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adapto...

Pfam Domains

PHaa 31–144UCSCPH domain
IRSaa 200–295UCSCPTB domain (IRS-1 type)

Gene Aliases

HGNC Name

insulin receptor substrate 2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_003749.3
p.A701_V702ins0
c.2102_2104dupCCG
Surrounding Variants
6 papers
NM_003749.3
p.A694del1
c.2080_2081delGGC
2 papers
NM_003749.3
p.A700_V702del0
c.2099_2104del6
2 papers
NM_003749.3
p.A699_V702del0
c.2096_2104del9
1 paper
NM_003749.3
p.A698_V702del0
c.2093_2104del12
2 papers
NM_003749.3
p.V702ins1
c.2104_2105insCCG
4 papers
NM_003749.3
p.V702ins2
c.2104_2105ins6
1 paper
NM_003749.3
p.A701_V702ins1
c.2103_2104insGCC
1 paper
NM_003749.3
p.A701_V702del2
c.2101_2105del6
1 paper
NM_003749.3
p.A699_V702del4
c.2095_2105del12
1 paper
NM_003749.3
p.A701ins1
c.2101_2102insTCG
2 papers
NM_003749.3
p.A700S
c.2098G>T
1 paper
NM_003749.3
p.A698T
c.2092G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."