Varaico: Literature-Extracted Genetic Variants

Gene:IRS2
Variant:p.D568N

IRS2

613 papers

RefSeq Summary

This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adapto...

Pfam Domains

PHaa 31–144UCSCPH domain
IRSaa 200–295UCSCPTB domain (IRS-1 type)

Gene Aliases

HGNC Name

insulin receptor substrate 2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003749.3
p.D568N
c.1702G>A
Surrounding Variants
1 paper
NM_003749.3
p.V559_Q565del0
c.1675_1695del21
1 paper
NM_003749.3
p.Q565P
c.1694A>C
1 paper
NM_003749.3
p.A564V
c.1691C>T
1 paper
NM_003749.3
p.R572C
c.1714C>T
1 paper
NM_003749.3
p.R554_A563del0
c.1662_1688del27
1 paper
NM_003749.3
p.A563V
c.1688C>T
1 paper
NM_003749.3
p.R558_R572del0
c.1673_1714del42
1 paper
NM_003749.3
p.R557_D562del0
c.1671_1685del15
1 paper
NM_003749.3
p.R557_D562del6
c.1669_1685del18
1 paper
NM_003749.3
p.R554_G561del0
c.1660_1683del24
1 paper
NM_003749.3
p.Y556_G561del0
c.1667_1681del15
1 paper
NM_003749.3
p.Y556_S560del0
c.1668_1679del12
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."