Varaico: Literature-Extracted Genetic Variants

Gene:IRS2
Variant:p.G536_G537del1

IRS2

613 papers

RefSeq Summary

This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adapto...

Pfam Domains

PHaa 31–144UCSCPH domain
IRSaa 200–295UCSCPTB domain (IRS-1 type)

Gene Aliases

HGNC Name

insulin receptor substrate 2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003749.3
p.G536_G537del1
c.1608_1610delCCG
Surrounding Variants
1 paper
NM_003749.3
p.G537V
c.1610G>T
1 paper
NM_003749.3
p.G536_G537del2
c.1606_1610del6
1 paper
NM_003749.3
p.G535G
c.1605C>T
1 paper
NM_003749.3
p.G533D
c.1598G>A
1 paper
NM_003749.3
p.D532G
c.1595A>G
1 paper
NM_003749.3
p.R531P
c.1592G>C
1 paper
NM_003749.3
p.H516_A530delFs
c.1547_1590del44
1 paper
NM_003749.3
p.A525V
c.1574C>T
1 paper
NM_003749.3
p.H551D
c.1651C>G
3 papers
NM_003749.3
p.I524V
c.1570A>G
1 paper
NM_003749.3
p.E522E
c.1566G>A
1 paper
NM_003749.3
p.R554C
c.1660C>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."