Varaico: Literature-Extracted Genetic Variants

Gene:IRS2
Variant:p.N26insFs

IRS2

613 papers

RefSeq Summary

This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adapto...

Pfam Domains

PHaa 31–144UCSCPH domain
IRSaa 200–295UCSCPTB domain (IRS-1 type)

Gene Aliases

HGNC Name

insulin receptor substrate 2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003749.3
p.N26insFs
c.77dupA
Surrounding Variants
1 paper
NM_003749.3
p.N26ins1
c.76_77insCCA
1 paper
NM_003749.3
p.N25N
c.75C>T
1 paper
NM_003749.3
p.N27insFs
c.79dupA
7 papers
NM_003749.3
p.N28_H29ins1
c.84_85insAAC
1 paper
NM_003749.3
p.N28ins0
c.82_84dupAAC
1 paper
NM_003749.3
p.H29N
c.85C>A
4 papers
NM_003749.3
p.N28del1
c.82_83delGTT
1 paper
NM_003749.3
p.N27_N28del2
c.79_83del6
1 paper
NM_003749.3
p.N26_N28del0
c.76_84del9
1 paper
NM_003749.3
p.H29L
c.86A>T
1 paper
NM_003749.3
p.N24H
c.70A>C
1 paper
NM_003749.3
p.S30G
c.88A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."