Varaico: Literature-Extracted Genetic Variants

Gene:IRS4
Variant:p.G584C

IRS4

161 papers

RefSeq Summary

IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been sho...

Pfam Domains

IRSaa 237–332UCSCPTB domain (IRS-1 type)

Gene Aliases

HGNC Name

insulin receptor substrate 4

HGNC Alias Symbols

PY160; IRS-4

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001379150.1
p.G584C
c.1750G>T
Surrounding Variants
1 paper
NM_001379150.1
p.G579D
c.1736G>A
1 paper
NM_001379150.1
p.G591S
c.1771G>A
1 paper
NM_001379150.1
p.G591fs
c.1771_1772fs
1 paper
NM_001379150.1
p.G591insFs
c.1772_1773insT
5 papers
NM_001379150.1
p.G591insFs
c.1772dupG
3 papers
NM_001379150.1
p.G591fs
c.1771_1772fs
3 papers
NM_001379150.1
p.G591delFs
c.1772delC
7 papers
NM_001379150.1
p.K592fs
c.1774_1775fs
1 paper
NM_001379150.1
p.K592fs
c.1774_1775fs
1 paper
NM_001379150.1
p.G573V
c.1718G>T
2 papers
NM_001379150.1
p.G572fs
c.1714_1715fs
1 paper
NM_001379150.1
p.G572R
c.1714G>C
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