Varaico: Literature-Extracted Genetic Variants

Gene:IRX2
Variant:p.K453R

IRX2

47 papers

RefSeq Summary

IRX2 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.[supplied by OMIM, Apr 2004].

Pfam Domains

Homeobox_KNaa 132–171UCSCHomeobox KN domain

Gene Aliases

HGNC Name

iroquois homeobox 2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_033267.5
p.K453R
c.1358A>G
Surrounding Variants
1 paper
NM_033267.5
p.P438L
c.1313C>T
1 paper
NM_033267.5
p.A431A
c.1293G>A
1 paper
NM_033267.5
p.A413V
c.1238C>T
1 paper
NM_033267.5
p.R409Q
c.1226G>A
1 paper
NM_033267.5
p.A361T
c.1081G>A
1 paper
NM_033267.5
p.P360A
c.1078C>G
1 paper
NM_033267.5
p.P347S
c.1039C>T
1 paper
NM_033267.5
p.K281T
c.842A>C
1 paper
NM_033267.5
p.D266V
c.797A>T
1 paper
NM_033267.5
p.D266N
c.796G>A
1 paper
NM_033267.5
p.D265A
c.794A>C
4 papers
NM_033267.5
p.E255D
c.765G>T
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