Varaico: Literature-Extracted Genetic Variants

ITGA4

153 papers

RefSeq Summary

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surfa...

Pfam Domains

FG-GAPaa 306–342UCSCFG-GAP repeat

FG-GAPaa 368–403UCSCFG-GAP repeat

Integrin_A_Ig_1aa 463–621UCSCIntegrin alpha Ig-like domain 1

Integrin_A_Ig_2aa 622–770UCSCIntegrin alpha Ig-like domain 2

Integrin_A_Ig_3aa 776–966UCSCIntegrin alpha Ig-like domain 3

Gene Aliases

HGNC Name

integrin subunit alpha 4

HGNC Previous Symbol

CD49D

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000885.6

p.K566K

c.1698A>G

Surrounding Variants

1 paper

NM_000885.6

p.R569W

c.1705C>T

1 paper

NM_000885.6

p.I571M

c.1713C>G

1 paper

NM_000885.6

p.T573I

c.1718C>T

1 paper

NM_000885.6

p.H582N

c.1744C>A

1 paper

NM_000885.6

p.R591*

c.1771C>T

2 papers

NM_000885.6

p.T615T

c.1845A>G

1 paper

NM_000885.6

p.E625K

c.1873G>A

1 paper

NM_000885.6

p.S628P

c.1882T>C