Varaico: Literature-Extracted Genetic Variants

ITGAM

620 papers

RefSeq Summary

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with ...

Pfam Domains

VWAaa 150–327UCSCvon Willebrand factor type A domain

FG-GAPaa 457–494UCSCFG-GAP repeat

FG-GAPaa 520–555UCSCFG-GAP repeat

Integrin_A_Ig_1aa 614–769UCSCIntegrin alpha Ig-like domain 1

Integrin_A_Ig_2aa 770–921UCSCIntegrin alpha Ig-like domain 2

ITGAX-like_Ig_3aa 922–1101UCSCIntegrin alpha-X-like, Ig-like domain 3

Gene Aliases

HGNC Name

integrin subunit alpha M

HGNC Previous Symbols

CR3A; CD11B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000632.4

p.L8fs

c.22_23fs

Surrounding Variants

1 paper

NM_000632.4

p.L8insFs

c.23dupT

2 papers

NM_000632.4

p.T9K

c.26C>A

1 paper

NM_000632.4

p.V5D

c.14T>A

1 paper

NM_000632.4

p.V5F

c.13G>T

1 paper

NM_000632.4

p.L3V

c.7C>G

2 papers

NM_000632.4

p.M1I

c.3G>A

1 paper

NM_000632.4

p.M1T

c.2T>C

1 paper

NM_000632.4

p.M1V

c.1A>G

1 paper

NM_000632.4

p.A10Splc

c.29-2A>T

1 paper

NM_000632.4

p.L13F

c.39A>C

1 paper

NM_000632.4

p.N18I

c.53A>T

1 paper

NM_000632.4

p.L19S

c.56T>C