Varaico: Literature-Extracted Genetic Variants

ITGAM

620 papers

RefSeq Summary

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with ...

Pfam Domains

VWAaa 150–327UCSCvon Willebrand factor type A domain

FG-GAPaa 457–494UCSCFG-GAP repeat

FG-GAPaa 520–555UCSCFG-GAP repeat

Integrin_A_Ig_1aa 614–769UCSCIntegrin alpha Ig-like domain 1

Integrin_A_Ig_2aa 770–921UCSCIntegrin alpha Ig-like domain 2

ITGAX-like_Ig_3aa 922–1101UCSCIntegrin alpha-X-like, Ig-like domain 3

Gene Aliases

HGNC Name

integrin subunit alpha M

HGNC Previous Symbols

CR3A; CD11B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

71 papers

NM_000632.4

p.R77H

c.230G>A

Surrounding Variants

1 paper

NM_000632.4

p.I76_V80delFs

c.228_238del11

1 paper

NM_000632.4

p.P75T

c.223C>A

1 paper

NM_000632.4

p.E74insFs

c.221_222insA

1 paper

NM_000632.4

p.V80Splc

c.238+7C>T

1 paper

NM_000632.4

p.Y68C

c.203A>G

1 paper

NM_000632.4

p.Y68F

c.203A>T

1 paper

NM_000632.4

p.Q65R

c.194A>G

1 paper

NM_000632.4

p.Q65L

c.194A>T

1 paper

NM_000632.4

p.Y64N

c.190T>A

1 paper

NM_000632.4

p.A57V

c.170C>T

1 paper

NM_000632.4

p.V55E

c.164T>A

1 paper

NM_000632.4

p.Q52fs

c.154_155fs