Varaico: Literature-Extracted Genetic Variants

ITGAM

620 papers

RefSeq Summary

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with ...

Pfam Domains

VWAaa 150–327UCSCvon Willebrand factor type A domain

FG-GAPaa 457–494UCSCFG-GAP repeat

FG-GAPaa 520–555UCSCFG-GAP repeat

Integrin_A_Ig_1aa 614–769UCSCIntegrin alpha Ig-like domain 1

Integrin_A_Ig_2aa 770–921UCSCIntegrin alpha Ig-like domain 2

ITGAX-like_Ig_3aa 922–1101UCSCIntegrin alpha-X-like, Ig-like domain 3

Gene Aliases

HGNC Name

integrin subunit alpha M

HGNC Previous Symbols

CR3A; CD11B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000632.4

p.A140fs

c.418_419fs

Surrounding Variants

1 paper

NM_000632.4

p.R142Q

c.425G>A

1 paper

NM_000632.4

p.N129K

c.387C>A

1 paper

NM_000632.4

p.N129K

c.387C>G

1 paper

NM_000632.4

p.F124C

c.371T>G

2 papers

NM_000632.4

p.E115V

c.344A>T

1 paper

NM_000632.4

p.G106G

c.318T>A

1 paper

NM_000632.4

p.P107delFs

c.320delC

1 paper

NM_000632.4

p.G106R

c.316G>C

2 papers

NM_000632.4

p.L103_A104Splc

c.310-6C>A

1 paper

NM_000632.4

p.L103L

c.307C>T

1 paper

NM_000632.4

p.L102V

c.304C>G

1 paper

NM_000632.4

p.P99S

c.295C>T