Varaico: Literature-Extracted Genetic Variants

ITGAM

620 papers

RefSeq Summary

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with ...

Pfam Domains

VWAaa 150–327UCSCvon Willebrand factor type A domain

FG-GAPaa 457–494UCSCFG-GAP repeat

FG-GAPaa 520–555UCSCFG-GAP repeat

Integrin_A_Ig_1aa 614–769UCSCIntegrin alpha Ig-like domain 1

Integrin_A_Ig_2aa 770–921UCSCIntegrin alpha Ig-like domain 2

ITGAX-like_Ig_3aa 922–1101UCSCIntegrin alpha-X-like, Ig-like domain 3

Gene Aliases

HGNC Name

integrin subunit alpha M

HGNC Previous Symbols

CR3A; CD11B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000632.4

p.R167P

c.500G>C

Surrounding Variants

1 paper

NM_000632.4

p.R167L

c.500G>T

1 paper

NM_000632.4

p.R168W

c.502C>T

1 paper

NM_000632.4

p.R168Q

c.503G>A

1 paper

NM_000632.4

p.D165G

c.494A>G

1 paper

NM_000632.4

p.M169I

c.507G>A

1 paper

NM_000632.4

p.M169I

c.507G>C

1 paper

NM_000632.4

p.M169I

c.507G>T

1 paper

NM_000632.4

p.V173G

c.518T>G

1 paper

NM_000632.4

p.T175I

c.524C>T

2 papers

NM_000632.4

p.S158A

c.472T>G

1 paper

NM_000632.4

p.D156A

c.467A>C

1 paper

NM_000632.4

p.K181I

c.542A>T