Varaico: Literature-Extracted Genetic Variants

ITGAM

620 papers

RefSeq Summary

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with ...

Pfam Domains

VWAaa 150–327UCSCvon Willebrand factor type A domain

FG-GAPaa 457–494UCSCFG-GAP repeat

FG-GAPaa 520–555UCSCFG-GAP repeat

Integrin_A_Ig_1aa 614–769UCSCIntegrin alpha Ig-like domain 1

Integrin_A_Ig_2aa 770–921UCSCIntegrin alpha Ig-like domain 2

ITGAX-like_Ig_3aa 922–1101UCSCIntegrin alpha-X-like, Ig-like domain 3

Gene Aliases

HGNC Name

integrin subunit alpha M

HGNC Previous Symbols

CR3A; CD11B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000632.4

p.A402delFs

c.1205delC

Surrounding Variants

1 paper

NM_000632.4

p.A402delFs

c.1206delT

1 paper

NM_000632.4

p.D396N

c.1186G>A

1 paper

NM_000632.4

p.A375P

c.1123G>C

1 paper

NM_000632.4

p.Y372Y

c.1116T>C

1 paper

NM_000632.4

p.G370G

c.1110G>A

1 paper

NM_000632.4

p.T368S

c.1103C>G

1 paper

NM_000632.4

p.T368S

c.1102A>T

3 papers

NM_000632.4

p.S367R

c.1101C>A

2 papers

NM_000632.4

p.G363_T368del0

c.1089_1103del15

2 papers

NM_000632.4

p.E353K

c.1057G>A

1 paper

NM_000632.4

p.S342insFs

c.1025_1026ins4

1 paper

NM_000632.4

p.G341R

c.1021G>C