Varaico: Literature-Extracted Genetic Variants

ITGAM

620 papers

RefSeq Summary

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with ...

Pfam Domains

VWAaa 150–327UCSCvon Willebrand factor type A domain

FG-GAPaa 457–494UCSCFG-GAP repeat

FG-GAPaa 520–555UCSCFG-GAP repeat

Integrin_A_Ig_1aa 614–769UCSCIntegrin alpha Ig-like domain 1

Integrin_A_Ig_2aa 770–921UCSCIntegrin alpha Ig-like domain 2

ITGAX-like_Ig_3aa 922–1101UCSCIntegrin alpha-X-like, Ig-like domain 3

Gene Aliases

HGNC Name

integrin subunit alpha M

HGNC Previous Symbols

CR3A; CD11B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000632.4

p.L780_S781insA

c.2338_2342ins3

Surrounding Variants

1 paper

NM_000632.4

p.I775V

c.2323A>G

1 paper

NM_000632.4

p.F766_K768del3

c.2296_2303del9

1 paper

NM_000632.4

p.P765S

c.2293C>T

1 paper

NM_000632.4

p.Q757*

c.2269C>T

1 paper

NM_000632.4

p.C791S

c.2372G>C

1 paper

NM_000632.4

p.R732_L733insG

c.2194_2198ins3

1 paper

NM_000632.4

p.P728delFs

c.2184delC

1 paper

NM_000632.4

p.I722I

c.2166C>T

1 paper

NM_000632.4

p.C721C

c.2163C>T

1 paper

NM_000632.4

p.S827S

c.2481C>A

1 paper

NM_000632.4

p.K830R

c.2489A>G

1 paper

NM_000632.4

p.T833M

c.2498C>T