Varaico: Literature-Extracted Genetic Variants

ITGAM

620 papers

RefSeq Summary

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with ...

Pfam Domains

VWAaa 150–327UCSCvon Willebrand factor type A domain

FG-GAPaa 457–494UCSCFG-GAP repeat

FG-GAPaa 520–555UCSCFG-GAP repeat

Integrin_A_Ig_1aa 614–769UCSCIntegrin alpha Ig-like domain 1

Integrin_A_Ig_2aa 770–921UCSCIntegrin alpha Ig-like domain 2

ITGAX-like_Ig_3aa 922–1101UCSCIntegrin alpha-X-like, Ig-like domain 3

Gene Aliases

HGNC Name

integrin subunit alpha M

HGNC Previous Symbols

CR3A; CD11B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000632.4

p.F971L

c.2911T>C

Surrounding Variants

2 papers

NM_000632.4

p.F971L

c.2913C>A

2 papers

NM_000632.4

p.F971L

c.2913C>G

1 paper

NM_000632.4

p.V975I

c.2923G>A

1 paper

NM_000632.4

p.W983*

c.2949G>A

1 paper

NM_000632.4

p.D984N

c.2950G>A

3 papers

NM_000632.4

p.T1000N

c.2999C>A

1 paper

NM_000632.4

p.E1002*

c.3004G>T

1 paper

NM_000632.4

p.H1007insFs

c.3020_3021insC

1 paper

NM_000632.4

p.S1008A

c.3022T>G

1 paper

NM_001145808.2

p.P1019L

c.3056C>T

1 paper

NM_000632.4

p.N1021D

c.3061A>G

1 paper

NM_000632.4

p.A1025_V1026ins4

c.3073_3077ins12