Varaico: Literature-Extracted Genetic Variants

ITGB3

785 papers

RefSeq Summary

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners ...

Pfam Domains

PSI_integrinaa 29–76UCSCIntegrin plexin domain

Integrin_betaaa 133–381UCSCIntegrin beta chain VWA domain

I-EGF_1aa 463–492UCSCIntegrin beta epidermal growth factor like domain 1

EGF_integrinaa 506–548UCSCIntegrin EGF domain

EGF_2aa 593–624UCSCEGF-like domain

Integrin_B_tailaa 632–717UCSCIntegrin beta tail domain

Gene Aliases

HGNC Name

integrin subunit beta 3

HGNC Previous Symbol

GP3A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000212.3

p.D591D

c.1773C>T

Surrounding Variants

1 paper

NM_000212.3

p.D591A

c.1772A>C

1 paper

NM_000212.3

p.D591H

c.1771G>C

1 paper

NM_000212.3

p.T592T

c.1776C>T

1 paper

NM_000212.3

p.T590A

c.1768A>G

1 paper

NM_000212.3

p.M594V

c.1780A>G

1 paper

NM_000212.3

p.S595fs

c.1783_1784fs

1 paper

NM_000212.3

p.T587T

c.1761C>T

1 paper

NM_000212.3

p.T587S

c.1760C>G

1 paper

NM_000212.3

p.T587S

c.1759A>T

1 paper

NM_000212.3

p.C586F

c.1757G>T

1 paper

NM_000212.3

p.N597delFs

c.1791delT

3 papers

NM_000212.3

p.C586R

c.1756T>C