Varaico: Literature-Extracted Genetic Variants

KAT2B

340 papers

RefSeq Summary

CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein enco...

Pfam Domains

PCAF_Naa 74–326UCSCPCAF (P300/CBP-associated factor) N-terminal domain

Acetyltransf_1aa 512–622UCSCAcetyltransferase (GNAT) family

Bromodomainaa 732–815UCSCBromodomain

Gene Aliases

HGNC Name

lysine acetyltransferase 2B

HGNC Previous Symbol

PCAF

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_003884.5

p.R653W

c.1957C>T

Surrounding Variants

3 papers

NM_003884.5

p.T657K

c.1970C>A

1 paper

NM_003884.5

p.A643V

c.1928C>T

1 paper

NM_003884.5

p.E668K

c.2002G>A

1 paper

NM_003884.5

p.K630T

c.1889A>C

1 paper

NM_003884.5

p.G615R

c.1843G>A

2 papers

NM_003884.5

p.D610A

c.1829A>C

1 paper

NM_003884.5

p.D601A

c.1802A>C

1 paper

NM_003884.5

p.H592Y

c.1774C>T

1 paper

NM_003884.5

p.T587I

c.1760C>T

1 paper

NM_003884.5

p.Y585N

c.1753T>A

1 paper

NM_003884.5

p.R682Q

c.2045G>A

1 paper

NM_003884.5

p.S689T

c.2065T>A