Varaico: Literature-Extracted Genetic Variants

Gene:KCNK4
Variant:p.V219M

KCNK4

74 papers

RefSeq Summary

This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. Thi...

Pfam Domains

Ion_trans_2aa 72–144UCSCIon channel
Ion_trans_2aa 173–259UCSCIon channel

Gene Aliases

HGNC Name

potassium two pore domain channel subfamily K member 4

HGNC Alias Symbols

K2p4.1; TRAAK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_033310.3
p.V219M
c.655G>A
Surrounding Variants
3 papers
NM_033310.3
p.G221S
c.661G>A
1 paper
NM_033310.3
p.D217N
c.649G>A
1 paper
NM_033310.3
p.V213M
c.637G>A
1 paper
NM_033310.3
p.T209R
c.626C>G
1 paper
NM_033310.3
p.I207T
c.620T>C
1 paper
NM_033310.3
p.V206I
c.616G>A
1 paper
NM_033310.3
p.V206L
c.616G>C
1 paper
NM_033310.3
p.I203T
c.608T>C
1 paper
NM_033310.3
p.I203V
c.607A>G
1 paper
NM_033310.3
p.E201G
c.602A>G
1 paper
NM_033310.3
p.K199N
c.597G>C
1 paper
NM_033310.3
p.K199N
c.597G>T
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