Varaico: Literature-Extracted Genetic Variants

KCNN4

142 papers

RefSeq Summary

The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpol...

Pfam Domains

SK_channelaa 11–126UCSCCalcium-activated SK potassium channel

Ion_trans_2aa 211–291UCSCIon channel

CaMBDaa 304–375UCSCCalmodulin binding domain

Gene Aliases

HGNC Name

potassium calcium-activated channel subfamily N member 4

HGNC Alias Symbols

KCa3.1; hSK4; hKCa4; hIKCa1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002250.3

p.V365A

c.1094T>C

Surrounding Variants

1 paper

NM_002250.3

p.Q364*

c.1090C>T

3 papers

NM_002250.3

p.S367A

c.1099T>G

2 papers

NM_002250.3

p.S367T

c.1099T>A

1 paper

NM_002250.3

p.E363D

c.1089A>T

1 paper

NM_002250.3

p.E363D

c.1089A>C

1 paper

NM_002250.3

p.S367C

c.1100C>G

1 paper

NM_002250.3

p.M368L

c.1102A>T

1 paper

NM_002250.3

p.M368L

c.1102A>C

1 paper

NM_002250.3

p.M368R

c.1103T>G

1 paper

NM_002250.3

p.M368T

c.1103T>C

1 paper

NM_002250.3

p.R362W

c.1084C>T

3 papers

NM_002250.3

p.S372A

c.1114T>G