Varaico: Literature-Extracted Genetic Variants

KCNN4

142 papers

RefSeq Summary

The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpol...

Pfam Domains

SK_channelaa 11–126UCSCCalcium-activated SK potassium channel

Ion_trans_2aa 211–291UCSCIon channel

CaMBDaa 304–375UCSCCalmodulin binding domain

Gene Aliases

HGNC Name

potassium calcium-activated channel subfamily N member 4

HGNC Alias Symbols

KCa3.1; hSK4; hKCa4; hIKCa1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002250.3

p.D130G

c.389A>G

Surrounding Variants

1 paper

NM_002250.3

p.L131I

c.391T>A

1 paper

NM_002250.3

p.C127R

c.379T>C

1 paper

NM_002250.3

p.P121S

c.361C>T

1 paper

NM_002250.3

p.G143E

c.428G>A

1 paper

NM_002250.3

p.G116V

c.347G>T

1 paper

NM_002250.3

p.G146C

c.436G>T

1 paper

NM_002250.3

p.G146R

c.436G>C

1 paper

NM_002250.3

p.V114L

c.340G>T

1 paper

NM_002250.3

p.V114L

c.340G>C

1 paper

NM_002250.3

p.V113L

c.337G>T

1 paper

NM_002250.3

p.V113L

c.337G>C

1 paper

NM_002250.3

p.Y161C

c.482A>G