Varaico: Literature-Extracted Genetic Variants

KDM1B

35 papers

RefSeq Summary

Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (Karytinos et al., 2009 [PubMed 1940...

Pfam Domains

zf-CWaa 138–191UCSCCW-type Zinc Finger

SWIRMaa 284–364UCSCSWIRM domain

Amino_oxidaseaa 392–820UCSCFlavin containing amine oxidoreductase

Gene Aliases

HGNC Name

lysine demethylase 1B

HGNC Previous Symbols

C6orf193; AOF1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001364614.2

p.D466N

c.1396G>A

Surrounding Variants

1 paper

NM_001364614.2

p.C451F

c.1352G>T

1 paper

NM_001364614.2

p.A448E

c.1343C>A

1 paper

NM_001364614.2

p.R416*

c.1246A>T

2 papers

NM_001364614.2

p.G394E

c.1181G>A

1 paper

NM_001364614.2

p.S529R

c.1587T>A