Varaico: Literature-Extracted Genetic Variants

KDM2B

145 papers

RefSeq Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin pr...

Pfam Domains

Cupin_8aa 119–337UCSCCupin-like domain

JHDaa 333–419UCSCJumonji helical domain

zf-CXXCaa 605–651UCSCCXXC zinc finger domain

PHD_4aa 656–723UCSCPHD-finger

Gene Aliases

HGNC Name

lysine demethylase 2B

HGNC Previous Symbol

FBXL10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_032590.5

p.A315V

c.944C>T

Surrounding Variants

3 papers

NM_032590.5

p.V316I

c.946G>A

2 papers

NM_032590.5

p.R349P

c.1046G>C

1 paper

NM_032590.5

p.Y370Y

c.1110C>T

1 paper

NM_032590.5

p.R377C

c.1129C>T