Varaico: Literature-Extracted Genetic Variants

KDM4A

135 papers

RefSeq Summary

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclea...

Pfam Domains

JmjNaa 15–49UCSCjmjN domain

JmjCaa 175–291UCSCJmjC domain, hydroxylase

PHD_2aa 732–767UCSCPHD-finger

zf-HC5HC2H_2aa 773–884UCSCPHD-zinc-finger like domain

Tudor_2aa 902–936UCSCJumonji domain-containing protein 2A Tudor domain

Tudor_2aa 960–994UCSCJumonji domain-containing protein 2A Tudor domain

Gene Aliases

HGNC Name

lysine demethylase 4A

HGNC Previous Symbols

JMJD2; JMJD2A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014663.3

p.K471T

c.1412A>C

Surrounding Variants

1 paper

NM_014663.3

p.D476E

c.1428T>A

1 paper

NM_014663.3

p.D476E

c.1428T>G

1 paper

NM_014663.3

p.K463Q

c.1387A>C

10 papers

NM_014663.3

p.A482E

c.1445C>A

1 paper

NM_014663.3

p.S457C

c.1370C>G

1 paper

NM_014663.3

p.A493V

c.1478C>T

1 paper

NM_014663.3

p.R498C

c.1492C>T

1 paper

NM_014663.3

p.R498H

c.1493G>A

1 paper

NM_014663.3

p.G503V

c.1508G>T

1 paper

NM_014663.3

p.K505I

c.1514A>T

1 paper

NM_014663.3

p.R518W

c.1552C>T

1 paper

NM_014663.3

p.C533C

c.1599C>T