Varaico: Literature-Extracted Genetic Variants

KDM4A

135 papers

RefSeq Summary

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclea...

Pfam Domains

JmjNaa 15–49UCSCjmjN domain

JmjCaa 175–291UCSCJmjC domain, hydroxylase

PHD_2aa 732–767UCSCPHD-finger

zf-HC5HC2H_2aa 773–884UCSCPHD-zinc-finger like domain

Tudor_2aa 902–936UCSCJumonji domain-containing protein 2A Tudor domain

Tudor_2aa 960–994UCSCJumonji domain-containing protein 2A Tudor domain

Gene Aliases

HGNC Name

lysine demethylase 4A

HGNC Previous Symbols

JMJD2; JMJD2A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014663.3

p.K835N

c.2505G>T

Surrounding Variants

1 paper

NM_014663.3

p.K835N

c.2505G>C

1 paper

NM_014663.3

p.V876M

c.2626G>A

1 paper

NM_014663.3

p.R825C

c.2473C>T

1 paper

NM_014663.3

p.C798C

c.2394T>C

1 paper

NM_014663.3

p.W793G

c.2377T>G

1 paper

NM_014663.3

p.A892P

c.2674G>C

1 paper

NM_014663.3

p.A892S

c.2674G>T

1 paper

NM_014663.3

p.I899T

c.2696T>C

1 paper

NM_014663.3

p.E772Q

c.2314G>C

1 paper

NM_014663.3

p.R913L

c.2738G>T

1 paper

NM_014663.3

p.C763R

c.2287T>C

1 paper

NM_014663.3

p.Q916R

c.2747A>G