Varaico: Literature-Extracted Genetic Variants

KDM4C

135 papers

RefSeq Summary

This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated for...

Pfam Domains

JmjNaa 17–51UCSCjmjN domain

JmjCaa 177–293UCSCJmjC domain, hydroxylase

PHD_2aa 712–747UCSCPHD-finger

zf-HC5HC2H_2aa 753–864UCSCPHD-zinc-finger like domain

Gene Aliases

HGNC Name

lysine demethylase 4C

HGNC Previous Symbol

JMJD2C

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_015061.6

p.L33R

c.98T>G

Surrounding Variants

1 paper

NM_015061.6

p.R27Q

c.80G>A

1 paper

NM_015061.6

p.R27W

c.79C>T

1 paper

NM_015061.6

p.H42R

c.125A>G

1 paper

NM_015061.6

p.R43C

c.127C>T

1 paper

NM_015061.6

p.P21delFs

c.61delC

1 paper

NM_015061.6

p.T18S

c.53C>G

NM_001146696.2

p.T40S

c.119C>G

1 paper

NM_015061.6

p.T18S

c.52A>T

1 paper

NM_015061.6

p.T18delFs

c.54delC

1 paper

NM_015061.6

p.M17V

c.49A>G

1 paper

NM_015061.6

p.A4S

c.10G>T

1 paper

NM_015061.6

p.V3V

c.9G>A

1 paper

NM_015061.6

p.V3L

c.7G>C