Varaico: Literature-Extracted Genetic Variants

KDM4C

135 papers

RefSeq Summary

This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated for...

Pfam Domains

JmjNaa 17–51UCSCjmjN domain

JmjCaa 177–293UCSCJmjC domain, hydroxylase

PHD_2aa 712–747UCSCPHD-finger

zf-HC5HC2H_2aa 753–864UCSCPHD-zinc-finger like domain

Gene Aliases

HGNC Name

lysine demethylase 4C

HGNC Previous Symbol

JMJD2C

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_015061.6

p.K208R

c.623A>G

Surrounding Variants

2 papers

NM_015061.6

p.E192A

c.575A>C

1 paper

NM_015061.6

p.H190L

c.569A>T

1 paper

NM_015061.6

p.L178F

c.532C>T

1 paper

NM_015061.6

p.P176L

c.527C>T

1 paper

NM_015061.6

p.T175N

c.524C>A

1 paper

NM_015061.6

p.V173G

c.518T>G

1 paper

NM_015061.6

p.D160N

c.478G>A

1 paper

NM_015061.6

p.R154R

c.462C>T

1 paper

NM_015061.6

p.R154H

c.461G>A