Varaico: Literature-Extracted Genetic Variants

KDM4C

135 papers

RefSeq Summary

This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated for...

Pfam Domains

JmjNaa 17–51UCSCjmjN domain

JmjCaa 177–293UCSCJmjC domain, hydroxylase

PHD_2aa 712–747UCSCPHD-finger

zf-HC5HC2H_2aa 753–864UCSCPHD-zinc-finger like domain

Gene Aliases

HGNC Name

lysine demethylase 4C

HGNC Previous Symbol

JMJD2C

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_015061.6

p.D396N

c.1186G>A

Surrounding Variants

1 paper

NM_015061.6

p.V395V

c.1185C>G

1 paper

NM_015061.6

p.D386N

c.1156G>A

1 paper

NM_015061.6

p.V412V

c.1236C>T

1 paper

NM_015061.6

p.S378F

c.1133C>T

1 paper

NM_015061.6

p.A418T

c.1252G>A

2 papers

NM_015061.6

p.F373L

c.1119C>A

2 papers

NM_015061.6

p.F373L

c.1119C>G

2 papers

NM_015061.6

p.F373L

c.1117T>C

1 paper

NM_015061.6

p.C455Y

c.1364G>A

1 paper

NM_015061.6

p.K465Q

c.1393A>C

1 paper

NM_015061.6

p.D469G

c.1406A>G

1 paper

NM_015061.6

p.S481_S482insFs

c.1443_1444insG